Japanese medaka (Oryzias latipes): developmental model for the study of alcohol teratology
نویسندگان
چکیده
منابع مشابه
The Japanese medaka, Oryzias latipes, as a new model organism for studying environmental germ-cell mutagenesis.
The effects of genotoxic substances on ecosystems should be assessed using various test systems with multiple genetic end points. The most widely used test system has been the specific-locus test developed by W.L. Russell, using the mouse. We are developing a new, nonmammalian test system using the Japanese medaka, Oryzias latipes. We have examined 625,926 embryos that correspond to 1,586,649 l...
متن کاملBetanodavirus infection in the freshwater model fish medaka (Oryzias latipes).
Betanodaviruses, the causal agents of viral nervous necrosis in marine fish, have bipartite, positive-sense RNA genomes. As their genomes are the smallest and simplest among viruses, betanodaviruses have been studied in detail as model viruses by using a genetic-engineering system, as has occurred with the insect alphanodaviruses, the other members of the family Nodaviridae. However, studies of...
متن کاملFitness components and ecological risk of transgenic release: a model using Japanese medaka (Oryzias latipes).
Any release of transgenic organisms into nature is a concern because ecological relationships between genetically engineered organisms and other organisms (including their wild-type conspecifics) are unknown. To address this concern, we developed a method to evaluate risk in which we input estimates of fitness parameters from a founder population into a recurrence model to predict changes in tr...
متن کاملA reproductive toxicology study of phenanthrene in medaka (Oryzias latipes).
Environmental contaminants, such as polycyclic aromatic hydrocarbons (PAHs), can disrupt the endocrine system and affect reproductive function of humans and wildlife. In this study, we exposed Japanese medaka (Oryzias latipes) to water-borne or food-spiked phenanthrene, an ubiquitous PAH, and investigated the chronic effects of the chemical on medaka reproduction. The results showed that phenan...
متن کاملEffects of the isoflavones genistein and equol on the gonadal development of Japanese medaka Oryzias latipes.
The estrogenic isoflavone compound genistein recently has been found in the effluents of sewage treatment plants and pulp mills, and the related compound equol has been detected in the runoff from agricultural fields treated with hog manure. Waterborne exposures of Japanese medaka (Oryzias latipes) to equol from soon after hatch to approximately 100 days posthatch induced gonadal intersex (i.e....
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ژورنال
عنوان ژورنال: Birth Defects Research Part B: Developmental and Reproductive Toxicology
سال: 2006
ISSN: 1542-9733,1542-9741
DOI: 10.1002/bdrb.20072